Chikungunya virus (CHIKV) is a mosquito-borne alphavirus that causes outbreaks of debilitating acute and chronic arthralgia in humans. There are currently no approved vaccines and few therapies against CHIKV. This antigen preparation is derived from a full length molecular clone based on a contemporary clinical CHIKV isolate and can be used to generate diagnostic reagents against CHIKV. Inactivated whole virion CHIKV antigen has the potential to screen patient or animal serum for the presence of CHIKV specific antibodies, act as an antigen for generating CHIKV specific monoclonal antibodies, or produce an inactivated vaccine against CHIKV.
If you are an academic institution or nonprofit organization interested in this research tool for noncommercial purposes, please contact the researcher directly to inquire about availability.
- Development of a highly protective combination monoclonal antibody therapy against Chikungunya virus PLoS Pathog 2013;9(4):e1003312