Office of Commercialization and Economic Development
Office of Technology Commercialization

Biomedical Data Repository for Literature-Based Drug Research and Discovery

Technology #10-0101

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Researchers
Alexander Tropsha
Managed By
Champ Gupton
Commercialization Manager 919.966.4132

A repository of terms extracted from the biomedical literature, named ChemoText, has been developed. ChemoText is designed specifically to be used in drug research and discovery, including predicting new uses for existing drugs or drug reprofiling. The repository is constructed by pulling the Medline annotations behind each PubMed record and extracting annotations that identify chemicals and indicate what biological activity and effects the chemicals have. The database can be seen as a network of relationships between chemicals, proteins, disease, and biological effects. 
Advantages:
•  Useful in drug research and discovery applications 
•  Designed to capture relationships between diseases, therapeutics and biology

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