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Biodegradable Elastomers for Medical Devices and Drug Delivery

Technology #06-0047

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Researchers
Valerie Ashby
Managed By
Jennifer Dean
919.966.3929
Patent Protection
US Patent US 8013061

Amorphous, polyester-based elastomers have been developed with tunable thermal and mechanical properties for applications in tissue engineering and drug delivery. Synthetic materials for biological applications must have similar mechanical properties to those of surrounding tissue to minimize irritation. Commonly used polymers suffer from rapid loss of mechanical properties upon degradation as well as large deformation. Shape-specific devices have been fabricated from this material.
Advantages:
•  Tunable mechanical properties and degradation rates
•  Amorphous structure enables linear degradation profile with minimal deformation
•  Easily fabricated into wide variety of shape-specific devices

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