EP3 is a receptor for prostaglandin 2. The EP3 receptor has been linked to prostaglandin-related processes such as pain, tumor growth and inflammation. These mice can be used to investigate the effects of EP3 modulators.
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- Urinary concentrating function in mice lacking EP3 receptors for prostaglandin E2 Am J Physiol 1998 Dec;275(6 Pt 2):F955-61